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Food allergies in preschool children
Tomíšková, Markéta ; Zlatohlávek, Lukáš (advisor) ; Sadílková, Aneta (referee)
1 Food allergies in children are common (affecting up to 8% of children) and their prevalence has been increasing in the last two to three decades. The basic measure for the long-term management of food allergy is an elimination diet, i.e. the exclusion of the relevant allergen from the diet. An elimination diet can disrupt and endanger healthy growth and development of a child. Therefore, it is important that elimination diets with a serious impact on the patient's diet are based on a medically confirmed diagnosis of food allergy. Preschool children eat to a significant extent outside their homes - 60 % of their diet is provided by the nursery school. The aim of the work is to provide parents of children with suspected or actual food allergy practical recommendations regarding their nutrition in the form of educational material, using the latest theoretical knowledge and with emphasis on food elimination only on the basis of proven food allergy and help to parents regarding nutrition of allergic children in nursery school. The main output of the work consists of educational material in Annex 2 of the thesis. The educational material will help to increase parents' awareness of food allergy and the need to confirm it by an allergist, especially in cases of risk of serious reactions and serious effects on the...
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Prevalence of food intolerance and allergy in the adult population of the Czech Republic
CHUDOBOVÁ TVRDÍKOVÁ, Marta
Purpose of this diploma thesis is mapping of prevalence of food intolerance and food allergy in the adult population. Theoretical part of the diploma thesis deals with the basic terms in this field - as are food intolerance, particular sorts of food intolerance, food allergy, crossed food allergies and also specific types of allergens. Next chapter describes adulthood from the aspect of developmental psychology and also from the legislative point of view. Further the general principles in case of food intolerance or food allergy are contained here. In the practical part, there was surveyed the prevalence of food intolerance or food allergy in the adult population. These data were obtained by means of a questionnaire of own construction. The questionnaire included 13 questions. In total 84 respondents took part in this questionnaire survey. From the results is evident that food intolerance or allergy appears mostly by women (72,6 %) - mainly in the population at the age of 18 - 28 years. The food allergy is the most frequent. According to the results milk, nuts and cereals belong to the frequent allergens. Gluten intolerance appears most frequently.
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Alpha-gal - dvě strany jedné mince
ŠABATKOVÁ, Klára
Ticks are interesting ectoparasites for their ability to modulate the host's defense response. This ability of tick saliva is often exploited by pathogens to increase their transmission. Therefore many researchers focused on identification of molecules in tick saliva and their possible medical use. This thesis focuses on the high natural presence of anti-Gal antibodies in human serum and it's interaction with alpha-gal epitope that is expressed on the surface of some pathogens and mammalian cells. This epitope has been identified in tick saliva and some drugs as well.
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Analysis of STAT 6 gene polymorphism by PCR-RFLP method
VADLEJCHOVÁ, Markéta
This work deals with the issue of allergies, especially food allergies which have a negative impact on the overall quality of life and whose prevalence is constantly increasing in developed countries. Reactions to some food allergens can even be life-threatening. Such allergens include, for example, nuts and peanuts. The development of allergies is influenced not only by environmental factors, but also by the individual genetic makeup of a particular individual. A key regulator of allergic diseases is the human STAT6 gene that is located on chromosome 12. Many polymorphisms have already been identified in this gene, one of which is the G/A SNP at position 2964 located in the 3´-untranslated region (rs324015). To analyze this polymorphism, DNA samples were taken from a total of 25 people from the Czech Republic, 16 of whom suffered from nut or peanut allergies. DNA isolation was performed from these samples and followed by PCR-RFLP. Electrophoresis was then performed, and individual genotypes were determined. DNA sequencing was also performed from some isolates to confirm the results obtained using PCR-RFLP. Genotype A/A was found in 4 %, A/G in 56 % and G/G in 40 % of examined persons; the frequency of alleles was 0.32 for A and 0.68 for G. The frequency of allele G was higher in people who had no allergies to nuts and peanuts.
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Food allergies in infant and toddler age
Stárková, Klára ; Floriánková, Marcela (advisor) ; El-Lababidi, Nabil (referee)
This bachelor thesis deals with the topic of food allergies in infant and toddler age. Theoretical part sums up the newest information about prevelance, which is increasing and food allergies are becoming one of the disease of civilization in 21. century. Next chapter is about the basics of patophysiology and explanation of difference between IgE and non-IgE reactions. Other chapters are focused on diagnostic methods, symptoms and treatment. Next parts deal with the most common food alergens in infant and toddler age, prognosis, risk factors and prevention. The aim of the work was to find out level of parent's knowlodege about the food allergies, what is their main source of the information and incidence of food allergies in children. The select methodology of the work was questionnare survey. The results are that parents don't have enough relevant information about food allergies, they are best informed about recommended lenght of an exclusive breastfeeding and about an appropriate age for an introduction of complementary food. The information are mostly searched on the internet, less from pediatrician. It was also found there is no significant dependency of the quality of information and level of education or allergic load in family. The proportion of children with food allergies was quite high...
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Calcium intake in children with cow's milk protein allergy
BÍLKOVÁ, Kateřina
The bachelor thesis deals with the calcium intake in children with cow's milk protein allergy from their diet. As the first aim I chose to inform parents about possibility of deficiency of the calcium intake in children with cow's milk protein allergy. The second aim is to find out the calcium content in the diet of children with this allergy. In the theoretical part of my bachelor thesis I briefly describe food allergy in general then I focuse on cow's milk protein allergy, types of reactions, symptoms, diagnostics and therapy. As the topic of this bachelor thesis is calcium intake in children with cow's milk protein allergy, the next part is devoted to calcium, its importance in human body, absorption, usability and also resources. At the end of theoretical part of this thesis I mention the specifics of nutrition in children with this allergy, such as different labeling of ingredients containing milk protein on food packaging or in composition of dishes, and also possibility of replacing milk and milk products in terms of consistency and taste. In the practical part of this bachelor thesis I cooperate with mothers of children with cow's milk protein allergy who give me one week menu of their children, from which I calculated the calcium intake for each day and also the average weekly calcium intake per day. I also informed these mothers about the possibility of calcium deficiency in their children's diet. Calcium intake approaching the recommended daily intake for a group of children aged 1-3 years occured only in one case. In four cases was the intake of calcium from children's diet lower than 50 % of the recommended daily intake for these children.
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Problematika kojení a vývoje imunitního systému u člověka
SPĚVÁKOVÁ, Markéta
The aim of this work is to evaluate breastfeeding along with the timing of complementary feeding of infants as a possible way of food allergy prevention. The first part of the thesis deals with the human immune system development and the factors which play a crucial role in this problematics. The next part is dedicated to breastfeeding and it describes the composition of breast milk and its immunological importance. The last part deals with the patophysiology of food allergies and food intolerance.
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The prevalence of nutrition intolerance by the adult population
CINEROVÁ, Leona
The Bachelor thesis dealing with the issue of food allergies and intolerance in the adult population. Its divided into theoretical and practical part. In the theoretical part the thesis deals with the term food allergy and intolerance as a whole structure. My Bachelor thesis explains their importance, describes their types, manifestations, possibilities of diagnostics and their treatment. The practical part using a questionnaire survey, maps the state of all food allergies and intolerances in the adult population, ascertains their knowledge from the respondents, the most common allergenic foods and their impact on affected individuals and last but not least, the attitude of families to eating habits with regard to allergenic foods. The sample of my 273 respondents showed the fact, that the knowledge of food allergy and nutrition intolerance, is rather below average and may cause food affects to the general public, but almost everyone of the affected people take this problem responsibly.
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Dietetic measures in children with cow's milk intolerance
SOLDÁTOVÁ, Kateřina
The thesis focuses on dietary measures for children suffering from intolerance to cow´s milk. This topic is still relevant since there is a continuous increase of children suffering from CMPA or lactose intolerance, and dietary measures serve as the elemental medical treatment. The purpose of the thesis was to become familiar with dietary measures suitable for children who are affected by the illness alongside with symptoms, diagnosis and the course of the intolerance to cow's milk. The thesis is divided into two parts, theoretical and practical one. The theoretical part describes the proper nutrition for children in the neonatal, infant and toddler age. Futher, it is stated what are the benefits of breastfeeding for both the baby and the mother, and what complications may cause the inability to breastfeed. Futhermore, the thesis describes in detail the composition of breast milk, cow's milk and the distribution of artificial milk. There is also the availability of the artifical milk for the Czech market introduced in the practical part. In addition, there are generally reported adverse reactions to food. In the section of adverse reactions to food I focus mainly on food allergy where I concentrate on CMPA. Simultaneously I focus on food intolerance where I describe lactose intolerance. The qualitative research method was used for the practical part of the work. It was executed with in-depth semi structured interviews with mothers of children suffering from the illness. These interviews consisted of two sets of questions. The first set of questions was aimed to mothers of children with CMPA and the second one to mothers of children with lactose intolerance. The research group contained 5 children from birth to age of 5 from South Bohemia and interviews were held with their mothers. These interviews were conducted anonymously and mothers of the children were identified as respondents no. 1 5. R1, R2 and R3 where mothers of children with CMPA and R4, R5 were mothers of children with lactose intolerance. To find respondents for the research the "snowball" method was used. Based on the goals of the thesis two research questions have been established. The first question dealt with how mothers were familiar with their children's diet and the illness itself. Research also revealed that almost all mothers were not satisfied with the approach of doctors to health problems of their children. Several mothers have even changed doctors. In most cases they searched for detailed information about the illness as well as dietary measures on the internet because the information received from the doctor were insufficient. Finally almost all of them investigated the worsening state of health by themselves serving given food to their children. Using this method the mothers found out whether the given food should have been omitted from the diet. The interviews have shown that all respondents have received at least brief background information from the general practitioner. The second question was, what were the components of diet for children suffering from the illness. In all the interviews, mothers of children with CMPA identically stated that they excluded all of mammalian milk and dairy products from their children's diet. Solely a breastfeeding mother eliminated these food products also from her diet. The research also revealed that all respondents eliminated other potencial allergenic foods from the diet. Two respondents also substituted calcium with tablets in their diet. Mothers of children with lactose intolerance consistently stated that they excluded all food and products that contained lactose from the child's diet and were still looking for what products and foods that could become a part of their child's diet. They also indicated that they had to stop breast-feeding a baby and establish a milk replacement in the form of low lactose artificial milk since their child had had health problems even when exclusive breastfeeding.
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Nutrition in children with chronic skin disease
Tomíšková, Markéta ; Zlatohlávek, Lukáš (advisor) ; Matoulek, Martin (referee)
1 Children and chronically ill are two groups of people with specific dietary requirements. Therefore, if the patient falls into both groups at the same time, it can be very difficult to determine a suitable nutritional plan for him/her and to determine the recommended diet. The aim of this thesis is to describe basic specifics and requirements for nutritional care for chronically ill children with skin diseases. In particular, this thesis focuses on the nutrition of children with atopic eczema. In the practical part of the thesis it was investigated how key findings of current research and recommendations of the Czech Paediatric Society are followed in practice and how the education of the patients related to atopic eczema is ensured. The conclusions of research and recommendations of the Czech Paediatric Society on exclusive breastfeeding lasting at least until the end of the 4th month have been respected in the majority of cases (85 %). Recommendations on the introduction of solid food around 6 months of age were also largely observed in the sample of patients studied - solid food was introduced later than in 6 months later in 23% of patients. Recommendations regarding elimination of food limited to proven allergens was mostly not respected. In 86% of patients 3-6 foods were eliminated. In 62% of...
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